BMP6P1

Across TCGA pan-cancer cohorts, BMP6P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of BMP6P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where BMP6P1 RNA is repressed in tumor relative to normal tissue. In most cancer types BMP6P1 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where BMP6P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BMP6P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.038	.013	4	view →
KIRC	Male	All	−0.035	<.001	4	view →
KICH	Male	III,IV	−0.067	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

BMP6P1–KIRP

Open the KIRP breakdown →