BMP5

Across TCGA patient cohorts, BMP5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,352 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BMP5-associated genes across cancer lineages are SLC8A3, CHRDL1, and ASPA. Each is linked with BMP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMP5-to-partner and partner-to-BMP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMP5 versus SLC8A3 in LUAD, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP5→partner) and Y-score (partner→BMP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC8A3 →	+0.324	+0.539	<.001	<.001	3	2
LSCC	CHRDL1 →	+1.324	+0.633	.004	.003	3	2
LUAD	ASPA →	+0.490	+0.510	<.001	.001	3	2
LSCC	SGCA →	+0.743	+0.593	<.001	<.001	3	2
LUAD	C7 →	+1.405	+0.632	<.001	<.001	3	2
LSCC	HSD11B1 →	+1.017	+0.653	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,352 associations by consensus.

BMP5 vs SLC8A3 — LUAD

Explore this scatter interactively →