BMP4

Across TCGA patient cohorts, BMP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,264 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BMP4-associated proteins across cancer lineages are LMCD1, SERPINF1, and HTRA1. Each is linked with BMP4 in more than 6 cancer types. Because this analysis shows association rather than direction, both BMP4-to-partner and partner-to-BMP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMP4 versus LMCD1 in OV, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP4→partner) and Y-score (partner→BMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LMCD1 →	+0.718	+0.916	<.001	<.001	3	7
OV	SERPINF1 →	+0.865	+1.242	<.001	<.001	3	6
BRCA	HTRA1 →	+1.195	+1.731	<.001	<.001	3	6
BRCA	ILK →	+0.512	+1.372	<.001	<.001	3	6
UCEC	ITGA1 →	+0.636	+1.418	<.001	<.001	3	6
BRCA	KANK2 →	+0.457	+1.231	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,264 associations by consensus.

BMP4 vs LMCD1 — OV

Explore this scatter interactively →