BMP2K

Across TCGA pan-cancer cohorts, BMP2K mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated BMP2K data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher BMP2K mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated BMP2K expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

GBM, COAD, and PDAC are the cancer types where BMP2K mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.419	0.632	.004	22	view →
COAD	DFS	Median	II,III,IV	0.875	1.000	.014	18	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LSCC	DFS	Median	All	0.892	1.000	.024	3	view →
HNSC	DFS	Quartile	III,IV	0.985	0.484	.036	2	view →
CCRCC	OS	Quartile	All	0.649	1.000	.009	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

BMP2K–GBM (OS)

Open the GBM breakdown →