BMP15

Across TCGA cell cohorts, BMP15 RNA expression is significantly associated with the mutation status of many other genes, with 157 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BMP15-associated genes across cancer lineages are DHX57, LAMA1, and ESRP1. Each is linked with BMP15 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMP15-to-partner and partner-to-BMP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DHX57 grouped by BMP15-low versus BMP15-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP15→partner) and Y-score (partner→BMP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DHX57 →	+5.029	+0.032	.006	<.001	3	2
BLOOD_Lymphoma	LAMA1 →	+2.769	+0.010	.004	<.001	3	2
BLOOD_Lymphoma	ESRP1 →	+4.643	+0.021	.005	<.001	3	2
BLOOD_Lymphoma	KIAA2026 →	+2.528	+0.009	.007	<.001	3	2
BLOOD_Lymphoma	LGR4 →	+5.643	+0.029	.002	<.001	3	2
OESOPHAGUS	CRB1 →	+4.906	+0.030	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 157 associations by consensus.

DHX57 by BMP15 expression — LUNG_SCLC

Explore this box plot interactively →