BMI1P1

Across TCGA pan-cancer cohorts, BMI1P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of BMI1P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where BMI1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BMI1P1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

BRCA and KIRP are the cancer types where BMI1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BMI1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.020	.006	4	view →
KIRP	Male	All	−0.011	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

BMI1P1–BRCA

Open the BRCA breakdown →