BMF

Across TCGA patient cohorts, BMF protein abundance is significantly associated with the RNA expression of many other genes, with 2,353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMF-associated genes across cancer lineages are SIGLEC6, TLE4, and TNFSF8. Each is linked with BMF in more than 2 cancer types. Because this analysis shows association rather than direction, both BMF-to-partner and partner-to-BMF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMF versus SIGLEC6 in CCRCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMF→partner) and Y-score (partner→BMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SIGLEC6 →	+0.521	+0.579	<.001	<.001	3	3
UCEC	TLE4 →	+0.637	+0.364	<.001	.001	3	2
CCRCC	TNFSF8 →	+0.696	+0.459	.002	.005	3	2
CCRCC	FBXW7 →	+0.447	+0.650	.002	<.001	3	2
LUAD	BLK →	+0.816	+0.701	<.001	.001	3	2
UCEC	KCNA6 →	+0.409	+0.484	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,353 associations by consensus.

BMF vs SIGLEC6 — CCRCC

Explore this scatter interactively →