BMERB1

Across TCGA patient cohorts, BMERB1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMERB1-associated genes across cancer lineages are Pericytes, Adipocytes, and Erythrocytes. Each is linked with BMERB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMERB1-to-partner and partner-to-BMERB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pericytes grouped by BMERB1-low versus BMERB1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMERB1→partner) and Y-score (partner→BMERB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Pericytes →	+0.037	+1.920	.002	.011	3	2
UCEC	Adipocytes →	+0.017	+2.096	.033	.016	3	1
UCEC	Erythrocytes →	+0.033	+2.393	.003	.017	3	1
UCEC	Keratinocytes →	-0.016	-1.871	.009	.035	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Pericytes by BMERB1 expression — UCEC

Explore this box plot interactively →