BLVRB

Across TCGA pan-cancer cohorts, BLVRB mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated BLVRB data layer compared with 20 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BLVRB mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated BLVRB expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

UCEC, LUAD, and HNSC are the cancer types where BLVRB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.350	1.000	.013	20	view →
LUAD	DFS	Quartile	III,IV	0.195	0.948	.006	11	view →
HNSC	DFS	Median	All	0.860	0.361	.022	7	view →
CCRCC	DFS	Median	All	0.851	0.633	.013	5	view →
GBM	OS	Tertile	All	0.934	0.740	.045	1	view →
LSCC	OS	Median	II,III,IV	0.810	1.000	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

BLVRB–UCEC (DFS)

Open the UCEC breakdown →