BLVRB

Across TCGA patient cohorts, BLVRB mutation is significantly associated with the RNA expression of many other genes, with 106 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLVRB-associated genes across cancer lineages are MIR4497, MIR5188, and LINC01764. Each is linked with BLVRB in more than 1 cancer types. Because this analysis shows association rather than direction, both BLVRB-to-partner and partner-to-BLVRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4497 grouped by BLVRB-low versus BLVRB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLVRB→partner) and Y-score (partner→BLVRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4497 →	+0.483	+3.551	<.001	<.001	3	1
UCEC	MIR5188 →	+0.884	+2.457	<.001	.005	3	1
UCEC	LINC01764 →	+0.518	+3.469	.001	.006	3	1
UCEC	CD24 →	+0.945	+3.225	.004	.009	3	1
UCEC	PIGA →	+0.682	+3.332	.002	.005	3	1
UCEC	SLC33A1 →	+0.620	+3.343	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 106 associations by consensus.

MIR4497 by BLVRB expression — UCEC

Explore this box plot interactively →