BLVRB

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BLVRB mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BLVRB-associated genes across cancer lineages are CD8+ Tem, Fibroblasts, and CD4+ T-cells. Each is linked with BLVRB in more than 1 cancer types. Because this analysis shows association rather than direction, both BLVRB-to-partner and partner-to-BLVRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tem grouped by BLVRB-low versus BLVRB-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLVRB→partner) and Y-score (partner→BLVRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCD8+ Tem →+0.055+7.954<.001.00831
HNSCFibroblasts →+0.033+5.339<.001.04731
HNSCCD4+ T-cells →+0.044+5.936<.001.03131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ Tem by BLVRB expression — HNSC

Box plot of CD8+ Tem in BLVRB-low vs BLVRB-high samples in HNSC.

Explore this box plot interactively →

Exploration