BLVRA

Across TCGA patient cohorts, BLVRA mutation is significantly associated with the RNA expression of many other genes, with 1,487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLVRA-associated genes across cancer lineages are MIR1224, LINC01974, and MIR3162. Each is linked with BLVRA in more than 2 cancer types. Because this analysis shows association rather than direction, both BLVRA-to-partner and partner-to-BLVRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1224 grouped by BLVRA-low versus BLVRA-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLVRA→partner) and Y-score (partner→BLVRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR1224 →	+0.589	+6.342	<.001	.001	3	3
CESC	LINC01974 →	+0.112	+5.103	<.001	.008	3	2
CESC	MIR3162 →	+0.406	+5.103	<.001	.008	3	2
SKCM	RNU6-644P →	+0.336	+2.913	.006	.003	3	2
SKCM	RNU2-51P →	+0.399	+3.763	.001	.003	3	2
SKCM	GNL2P1 →	+0.035	+2.823	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,487 associations by consensus.

MIR1224 by BLVRA expression — CESC

Explore this box plot interactively →