BLOC1S6

Across TCGA patient cohorts, BLOC1S6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,279 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BLOC1S6-associated proteins across cancer lineages are TP53BP1, UBR1, and NEDD4. Each is linked with BLOC1S6 in more than 6 cancer types. Because this analysis shows association rather than direction, both BLOC1S6-to-partner and partner-to-BLOC1S6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BLOC1S6 versus TP53BP1 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S6→partner) and Y-score (partner→BLOC1S6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TP53BP1 →	+0.443	+0.509	<.001	<.001	3	7
BRCA	UBR1 →	+0.240	+0.568	<.001	<.001	3	6
OV	NEDD4 →	+0.496	+0.643	<.001	<.001	3	5
BRCA	PEAK1 →	+0.257	+0.427	<.001	<.001	3	4
OV	CHST14 →	+0.490	+0.556	<.001	<.001	3	4
COAD	DDX28 →	-0.495	-0.551	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,279 associations by consensus.

BLOC1S6 vs TP53BP1 — BRCA

Explore this scatter interactively →