BLOC1S6

Across TCGA patient cohorts, BLOC1S6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,387 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BLOC1S6-associated genes across cancer lineages are SQOR, CREBL2, and CDKN2D. Each is linked with BLOC1S6 in more than 3 cancer types. Because this analysis shows association rather than direction, both BLOC1S6-to-partner and partner-to-BLOC1S6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BLOC1S6 versus SQOR in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S6→partner) and Y-score (partner→BLOC1S6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SQOR →	+0.679	+0.302	<.001	<.001	3	4
GBM	CREBL2 →	+0.397	+0.266	.001	.001	3	3
GBM	CDKN2D →	-0.511	-0.276	.001	.001	3	3
UCEC	SCEL →	-1.885	-0.360	<.001	<.001	3	3
UCEC	DUSP5 →	-1.272	-0.353	<.001	.004	3	3
UCEC	S100A8 →	-2.315	-0.412	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,387 associations by consensus.

BLOC1S6 vs SQOR — GBM

Explore this scatter interactively →