BLOC1S6

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BLOC1S6 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLOC1S6-associated genes across cancer lineages are Ku80. Each is linked with BLOC1S6 in more than 1 cancer types. Because this analysis shows association rather than direction, both BLOC1S6-to-partner and partner-to-BLOC1S6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by BLOC1S6-low versus BLOC1S6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S6→partner) and Y-score (partner→BLOC1S6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.319+2.820.027.03621
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Ku80 by BLOC1S6 expression — UCEC

Box plot of Ku80 in BLOC1S6-low vs BLOC1S6-high samples in UCEC.

Explore this box plot interactively →

Exploration