BLOC1S6

Across TCGA cell cohorts, BLOC1S6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,921 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BLOC1S6-associated GO terms across cancer lineages are Circadian sleep/wake cycle, Ubiquitin-dependent protein catabolic process via the N-end rule pathway, and Transcription elongation by RNA polymerase II. Each is linked with BLOC1S6 in more than 19 cancer types. Because this analysis shows association rather than direction, both BLOC1S6-to-partner and partner-to-BLOC1S6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Circadian sleep/wake cycle grouped by BLOC1S6-low versus BLOC1S6-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S6→partner) and Y-score (partner→BLOC1S6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Circadian sleep/wake cycle →	+0.170	+0.963	<.001	<.001	3	20
STOMACH	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.087	+0.842	<.001	<.001	3	16
LUNG_SCLC	Transcription elongation by RNA polymerase II →	+0.102	+0.494	<.001	.001	3	14
OVARY	Regulation of DNA damage checkpoint →	+0.089	+0.712	.001	.003	3	14
LARGE_INTESTINE	Positive regulation of t-circle formation →	-0.153	-0.586	<.001	<.001	3	13
LARGE_INTESTINE	Spindle assembly →	+0.078	+0.724	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,921 associations by consensus.

Circadian sleep/wake cycle by BLOC1S6 expression — OVARY

Explore this box plot interactively →