Across TCGA patient cohorts, BLOC1S3 mutation is significantly associated with the RNA expression of many other genes, with 459 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLOC1S3-associated genes across cancer lineages are RN7SKP224, MIR1302-2HG, and PPIAP5. Each is linked with BLOC1S3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BLOC1S3-to-partner and partner-to-BLOC1S3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S3→partner) and Y-score (partner→BLOC1S3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP224 →	+0.138	+2.811	.001	.004	3	2
COAD	MIR1302-2HG →	+0.044	+4.602	<.001	.008	3	1
COAD	PPIAP5 →	+0.225	+4.951	.001	.002	3	1
COAD	POLR3KP2 →	+0.207	+5.003	<.001	.004	3	1
UCEC	EME1 →	+0.625	+2.595	.006	.006	3	1
UCEC	NTAN1 →	+0.569	+2.638	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 459 associations by consensus.

Exploration

BLOC1S3 survival (RNA) · tumor vs normal (RNA) · all BLOC1S3 data types