Across TCGA patient cohorts, BLOC1S2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,187 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BLOC1S2-associated proteins across cancer lineages are GLRX3, NT5C2, and PAIP2B. Each is linked with BLOC1S2 in more than 5 cancer types. Because this analysis shows association rather than direction, both BLOC1S2-to-partner and partner-to-BLOC1S2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S2→partner) and Y-score (partner→BLOC1S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GLRX3 →	+0.296	+0.253	.001	.002	3	6
OV	NT5C2 →	+0.321	+0.453	<.001	<.001	3	5
PDAC	PAIP2B →	-0.622	-0.347	.003	<.001	3	4
COAD	SLK →	+0.345	+0.812	<.001	<.001	3	4
BRCA	XPNPEP1 →	+0.210	+0.311	.003	.001	3	4
GBM	NHLRC2 →	+0.244	+0.282	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,187 associations by consensus.

Exploration

BLOC1S2 survival (RNA) · tumor vs normal (RNA) · all BLOC1S2 data types