Across TCGA patient cohorts, BLOC1S2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,985 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BLOC1S2-associated genes across cancer lineages are CDC20, KIF15, and UBE2C. Each is linked with BLOC1S2 in more than 4 cancer types. Because this analysis shows association rather than direction, both BLOC1S2-to-partner and partner-to-BLOC1S2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S2→partner) and Y-score (partner→BLOC1S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDC20 →	-1.037	-0.168	<.001	<.001	3	5
GBM	KIF15 →	-1.097	-0.239	<.001	<.001	3	5
LUAD	UBE2C →	-1.771	-0.230	<.001	<.001	3	4
HNSC	VRK1 →	-0.896	-0.203	.003	<.001	3	4
HNSC	FAM83D →	-1.070	-0.219	<.001	<.001	3	4
HNSC	CEP72 →	-0.704	-0.139	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,985 associations by consensus.

Exploration

BLOC1S2 survival (RNA) · tumor vs normal (RNA) · all BLOC1S2 data types