BLOC1S2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BLOC1S2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,042 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible BLOC1S2-associated GO terms across cancer lineages are Regulation of endosome size, Regulation of lysosome size, and Embryonic brain development. Each is linked with BLOC1S2 in more than 10 cancer types. Because this analysis shows association rather than direction, both BLOC1S2-to-partner and partner-to-BLOC1S2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S2→partner) and Y-score (partner→BLOC1S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSRegulation of endosome size →+0.078+0.654.002<.001311
OVARYRegulation of lysosome size →+0.098+0.747.001.003311
SOFT_TISSUEEmbryonic brain development →+0.170+0.690<.001<.001310
PANCREASPositive regulation of mitochondrial ATP synthesis coupled electron transport →+0.107+0.574.001.00438
LARGE_INTESTINEGlucosamine metabolic process →+0.110+0.657<.001<.00138
UPPER_AERODIGESTIVE_TRACTRegulation of DNA damage checkpoint →+0.067+0.631<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,042 associations by consensus.

Exploration