BLNK

Across TCGA pan-cancer cohorts, BLNK RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of BLNK’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where BLNK RNA is repressed in tumor relative to normal tissue. In most cancer types BLNK is over-expressed in tumor, although a few such as KIRC and HNSC show the opposite, repressed pattern.

KIRC, HNSC, and KIRP are the cancer types where BLNK tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BLNK RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	−1.246	<.001	12	view →
HNSC	Male	II,III,IV	−1.494	<.001	11	view →
KIRP	All	II,III,IV	−1.156	<.001	9	view →
COAD	Female	All	−0.855	<.001	8	view →
THCA	Male	All	+0.742	<.001	7	view →
BRCA	All	III,IV	+1.131	<.001	6	view →
READ	All	II,III,IV	−1.865	.021	4	view →
UCEC	All	All	+1.034	.001	4	view →
LUAD	Female	All	+0.590	<.001	4	view →
LIHC	All	All	−0.479	.004	2	view →
LUSC	All	All	+0.361	.025	2	view →
PRAD	All	All	+0.309	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

BLNK–KIRC

Open the KIRC breakdown →