Across TCGA patient cohorts, BLM RNA expression is significantly associated with the protein abundance of many other proteins, with 25,743 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BLM-associated proteins across cancer lineages are NCAPG_S674, NCL_S67, and NUF2_S247. Each is linked with BLM in more than 9 cancer types. Because this analysis shows association rather than direction, both BLM-to-partner and partner-to-BLM results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BLM→partner) and Y-score (partner→BLM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCAPG_S674 →	+1.207	+0.793	<.001	<.001	3	10
LUAD	NCL_S67 →	+1.012	+0.845	<.001	<.001	3	10
OV	NUF2_S247 →	+1.514	+1.167	<.001	<.001	3	10
BRCA	KPNA2 →	+0.694	+0.671	<.001	<.001	3	10
UCEC	MAD2L1 →	+0.573	+0.905	<.001	<.001	3	10
OV	POLD1 →	+0.390	+1.029	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,743 associations by consensus.

Exploration

BLM survival (RNA) · tumor vs normal (RNA) · all BLM data types