BLID

Across TCGA patient cohorts, BLID mutation is significantly associated with the RNA expression of many other genes, with 1,079 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLID-associated genes across cancer lineages are SSXP4, RNU6-650P, and RNU6-13P. Each is linked with BLID in more than 1 cancer types. Because this analysis shows association rather than direction, both BLID-to-partner and partner-to-BLID results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSXP4 grouped by BLID-low versus BLID-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLID→partner) and Y-score (partner→BLID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SSXP4 →	+0.108	+6.924	<.001	<.001	3	2
LUAD	RNU6-650P →	+0.370	+5.742	<.001	<.001	3	2
LUAD	RNU6-13P →	+0.617	+5.037	<.001	.002	3	2
LUSC	RN7SL667P →	+0.162	+4.792	<.001	.006	3	2
SKCM	MIR5092 →	+0.404	+4.594	<.001	.008	3	2
UCEC	RNA5SP408 →	+0.292	+2.727	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,079 associations by consensus.

SSXP4 by BLID expression — LUAD

Explore this box plot interactively →