BLID

Across TCGA patient cohorts, BLID mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLID-associated genes across cancer lineages are p62 Lck ligand, Rab11, and S6_pS240_S244. Each is linked with BLID in more than 1 cancer types. Because this analysis shows association rather than direction, both BLID-to-partner and partner-to-BLID results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by BLID-low versus BLID-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLID→partner) and Y-score (partner→BLID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.462	+3.584	.003	.002	3	1
UCEC	Rab11 →	-0.156	-2.980	.026	.036	3	1
UCEC	S6_pS240_S244 →	+0.551	+2.459	.004	.020	3	1
UCEC	Annexin_VII →	-0.167	-2.459	.012	.020	3	1
UCEC	Caspase-8 →	-0.306	-3.143	.011	.018	3	1
UCEC	4E-BP1 →	+0.297	+2.837	.023	.035	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

p62 Lck ligand by BLID expression — UCEC

Explore this box plot interactively →