BLCAP

Across TCGA pan-cancer cohorts, BLCAP RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of BLCAP’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BLCAP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BLCAP is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

HNSC, KIRC, and COAD are the cancer types where BLCAP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BLCAP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.635	<.001	11	view →
KIRC	Male	II,III,IV	−0.613	<.001	11	view →
COAD	Male	II,III,IV	+0.678	<.001	9	view →
LUSC	Male	All	+0.794	<.001	8	view →
STAD	All	II,III,IV	+0.761	<.001	6	view →
BRCA	All	All	−0.634	<.001	6	view →
THCA	Male	III,IV	−0.521	<.001	5	view →
CHOL	All	All	+0.646	<.001	4	view →
LIHC	All	All	+0.330	.001	4	view →
BLCA	All	III,IV	+0.609	.011	3	view →
PAAD	All	All	+0.987	.035	2	view →
UCEC	All	All	−0.614	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

BLCAP–HNSC

Open the HNSC breakdown →