BIRC8

Across TCGA cell cohorts, BIRC8 RNA expression is significantly associated with the RNA expression of many other genes, with 739 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible BIRC8-associated genes across cancer lineages are PRG3, GPR101, and OR5AK2. Each is linked with BIRC8 in more than 2 cancer types. Because this analysis shows association rather than direction, both BIRC8-to-partner and partner-to-BIRC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BIRC8 versus PRG3 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.89.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BIRC8→partner) and Y-score (partner→BIRC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PRG3 →	+0.034	+0.019	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	GPR101 →	+0.144	+0.013	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR5AK2 →	+0.114	+0.019	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR52E8 →	+0.184	+0.019	<.001	<.001	3	3
LUNG_NSCLC_LUSC	OR2T2 →	+0.203	+0.019	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR2J2 →	+0.123	+0.007	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 739 associations by consensus.

BIRC8 vs PRG3 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →