BIRC7

Across TCGA patient cohorts, BIRC7 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,357 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BIRC7-associated proteins across cancer lineages are NPL, LIPA, and ADA2. Each is linked with BIRC7 in more than 4 cancer types. Because this analysis shows association rather than direction, both BIRC7-to-partner and partner-to-BIRC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BIRC7 versus NPL in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BIRC7→partner) and Y-score (partner→BIRC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NPL →	+0.679	+0.870	<.001	<.001	3	5
LSCC	LIPA →	+0.475	+0.614	<.001	<.001	3	4
UCEC	ADA2 →	+0.659	+1.183	<.001	<.001	3	4
UCEC	CAPG →	+0.473	+0.935	.002	.001	2	5
LSCC	GPNMB →	+0.632	+0.541	.001	.001	2	5
UCEC	IFI30 →	+0.415	+0.652	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,357 associations by consensus.

BIRC7 vs NPL — LSCC

Explore this scatter interactively →