BIRC7

Across TCGA patient cohorts, BIRC7 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,633 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BIRC7-associated proteins across cancer lineages are TCOF1_S1410, TSHZ1_S364, and CCDC97_S212. Each is linked with BIRC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both BIRC7-to-partner and partner-to-BIRC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BIRC7 versus TCOF1_S1410 in CCRCC, with a Pearson correlation of 0.59.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BIRC7→partner) and Y-score (partner→BIRC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TCOF1_S1410 →	+0.626	+0.296	.006	.003	1	1
CCRCC	TSHZ1_S364 →	-0.826	-0.296	.004	.003	1	1
CCRCC	CCDC97_S212 →	-0.400	-0.313	.004	.002	1	1
CCRCC	ERG_S81 →	-0.873	-0.273	.002	.008	1	1
CCRCC	FARP2_T430 →	-0.776	-0.296	<.001	.003	1	1
CCRCC	GNB3 →	-0.456	-0.313	.006	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,633 associations by consensus.

BIRC7 vs TCOF1_S1410 — CCRCC

Explore this scatter interactively →