BIRC7

Across TCGA cell cohorts, BIRC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,999 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BIRC7-associated GO terms across cancer lineages are Regulation of cellular component size, Protein localization to membrane raft, and Glycolipid catabolic process. Each is linked with BIRC7 in more than 5 cancer types. Because this analysis shows association rather than direction, both BIRC7-to-partner and partner-to-BIRC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cellular component size grouped by BIRC7-low versus BIRC7-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BIRC7→partner) and Y-score (partner→BIRC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of cellular component size →	+0.032	+0.439	.003	.001	3	6
OESOPHAGUS	Protein localization to membrane raft →	+0.253	+0.391	<.001	.008	2	6
SKIN	Glycolipid catabolic process →	+0.158	+3.598	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Regulation of myoblast fusion →	+0.057	+0.458	<.001	<.001	3	5
SKIN	Carbohydrate derivative catabolic process →	+0.041	+3.373	.003	<.001	3	5
PANCREAS	Positive regulation of neurogenesis →	+0.035	+0.183	.004	.007	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,999 associations by consensus.

Regulation of cellular component size by BIRC7 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →