BIN2

Across TCGA patient cohorts, BIN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,872 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BIN2-associated proteins across cancer lineages are MYO1F, MYO1G, and NADK. Each is linked with BIN2 in more than 9 cancer types. Because this analysis shows association rather than direction, both BIN2-to-partner and partner-to-BIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BIN2 versus MYO1F in GBM, with a Pearson correlation of 0.83.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BIN2→partner) and Y-score (partner→BIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1F →	+0.796	+1.020	<.001	<.001	3	10
GBM	MYO1G →	+0.700	+0.846	<.001	<.001	3	10
BRCA	NADK →	+0.502	+1.065	<.001	<.001	3	10
GBM	NAIP →	+0.763	+0.940	<.001	<.001	3	10
GBM	NCF1 →	+0.701	+0.832	<.001	<.001	3	10
OV	NECAP2 →	+0.374	+1.088	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,872 associations by consensus.

BIN2 vs MYO1F — GBM

Explore this scatter interactively →