BIN2

Across TCGA cell cohorts, BIN2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BIN2-associated genes across cancer lineages are C9orf92. Each is linked with BIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BIN2-to-partner and partner-to-BIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf92 grouped by BIN2-low versus BIN2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BIN2→partner) and Y-score (partner→BIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C9orf92 →	+0.194	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

C9orf92 by BIN2 expression — SOFT_TISSUE

Explore this box plot interactively →