BID

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BID protein abundance is significantly associated with the RNA expression of many other genes, with 2,753 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BID-associated genes across cancer lineages are SH3BP2, GBA, and ABCA2. Each is linked with BID in more than 4 cancer types. Because this analysis shows association rather than direction, both BID-to-partner and partner-to-BID results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BID versus SH3BP2 in BLOOD_Myeloma, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BID→partner) and Y-score (partner→BID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaSH3BP2 →+1.163+0.931.001.00535
CNSGBA →-0.901-0.996<.001.00135
BLOOD_LeukemiaABCA2 →+2.122+0.699<.001<.00135
BLOOD_MyelomaMRPL9 →+0.756+1.259.006.00235
STOMACHCHCHD4 →+1.035+1.330<.001.00235
BREASTCGN →+2.203+1.140<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,753 associations by consensus.

BID vs SH3BP2 — BLOOD_Myeloma

Per-sample scatter of BID vs SH3BP2 in BLOOD_Myeloma (Pearson r = 0.66).

Explore this scatter interactively →

Exploration