BICRA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BICRA RNA expression is significantly associated with the protein abundance of many other proteins, with 8,945 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BICRA-associated proteins across cancer lineages are TAF10, VCAN, and VCAN_S1349. Each is linked with BICRA in more than 2 cancer types. Because this analysis shows association rather than direction, both BICRA-to-partner and partner-to-BICRA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BICRA versus TAF10 in PDAC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BICRA→partner) and Y-score (partner→BICRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACTAF10 →+0.278+0.187.003.00633
OVVCAN →+1.160+0.897.001.00533
CCRCCVCAN_S1349 →+0.902+0.342.002.00133
CCRCCC1R →+0.640+0.343<.001<.00133
CCRCCDCN →+0.954+0.267.001.00833
GBMAKAP12_S248 →-0.786-0.419<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,945 associations by consensus.

BICRA vs TAF10 — PDAC

Per-sample scatter of BICRA vs TAF10 in PDAC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration