BICDL2

Across TCGA patient cohorts, BICDL2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,330 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BICDL2-associated genes across cancer lineages are PDZK1IP1, SDCBP2, and PGBD1. Each is linked with BICDL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both BICDL2-to-partner and partner-to-BICDL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BICDL2 versus PDZK1IP1 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICDL2→partner) and Y-score (partner→BICDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDZK1IP1 →	+1.640	+0.676	<.001	<.001	3	4
HNSC	SDCBP2 →	+1.327	+0.697	<.001	<.001	3	4
UCEC	PGBD1 →	-0.677	-0.553	<.001	<.001	3	4
OV	SH3RF2 →	+2.385	+2.054	.005	.005	3	4
LSCC	LIPH →	+1.019	+0.564	<.001	<.001	3	4
LSCC	PRSS22 →	+1.408	+0.538	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,330 associations by consensus.

BICDL2 vs PDZK1IP1 — LSCC

Explore this scatter interactively →