BICDL2

Across TCGA cell cohorts, BICDL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,473 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BICDL2-associated GO terms across cancer lineages are Response to indole-3-methanol, Calcium-independent cell-cell adhesion, and Desmosome assembly. Each is linked with BICDL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both BICDL2-to-partner and partner-to-BICDL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by BICDL2-low versus BICDL2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BICDL2→partner) and Y-score (partner→BICDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to indole-3-methanol →	+0.239	+2.717	<.001	<.001	3	13
LUNG_SCLC	Calcium-independent cell-cell adhesion →	+0.423	+1.516	.004	<.001	2	12
LUNG_NSCLC_LUSC	Desmosome assembly →	+0.403	+2.307	<.001	<.001	3	11
BREAST	Cellular response to indole-3-methanol →	+0.202	+2.594	<.001	<.001	2	12
OESOPHAGUS	Basolateral protein secretion →	+0.174	+2.653	.001	<.001	3	11
OESOPHAGUS	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.251	+3.176	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,473 associations by consensus.

Response to indole-3-methanol by BICDL2 expression — BREAST

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