BICDL2

Across TCGA cell cohorts, BICDL2 mutation is significantly associated with the RNA expression of many other genes, with 202 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BICDL2-associated genes across cancer lineages are MYF5, FSHB, and CFHR2. Each is linked with BICDL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BICDL2-to-partner and partner-to-BICDL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF5 grouped by BICDL2-low versus BICDL2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICDL2→partner) and Y-score (partner→BICDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MYF5 →	+0.749	+5.321	<.001	.005	3	1
CNS	FSHB →	+0.032	+5.321	<.001	.005	3	1
BLOOD_Leukemia	CFHR2 →	+0.245	+5.124	<.001	<.001	3	1
BREAST	LCN9 →	+0.072	+5.169	<.001	.005	3	1
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1
BREAST	PABPC1L2A →	+0.083	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 202 associations by consensus.

MYF5 by BICDL2 expression — CNS

Explore this box plot interactively →