Across TCGA cell cohorts, BICD2 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BICD2-associated genes across cancer lineages are DEFB4A, OR10W1, and LRRC3C. Each is linked with BICD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BICD2-to-partner and partner-to-BICD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICD2→partner) and Y-score (partner→BICD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DEFB4A →	+0.086	+3.269	<.001	.007	3	2
LARGE_INTESTINE	OR10W1 →	+0.012	+3.655	<.001	<.001	3	2
LARGE_INTESTINE	LRRC3C →	+0.234	+2.777	<.001	.002	3	2
BONE	OR1L6 →	+0.020	+5.169	<.001	.004	3	1
BONE	C2orf80 →	+0.126	+5.169	<.001	.004	3	1
SOFT_TISSUE	C20orf85 →	+0.115	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

BICD2 survival (RNA) · tumor vs normal (RNA) · all BICD2 data types