BICD1

Across TCGA patient cohorts, BICD1 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BICD1-associated genes across cancer lineages are eEF2, GAPDH, and Bak. Each is linked with BICD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BICD1-to-partner and partner-to-BICD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by BICD1-low versus BICD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICD1→partner) and Y-score (partner→BICD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.372	+2.700	.002	.006	3	2
UCEC	GAPDH →	+0.431	+2.000	.018	.029	3	2
UCEC	Bak →	+0.213	+1.584	.012	.034	3	2
UCEC	Di-Ras3 →	-0.135	-2.794	.007	.003	3	2
UCEC	EGFR_pY1068 →	-0.275	-2.807	.001	.002	3	1
UCEC	eIF4G →	+0.265	+1.906	.012	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

eEF2 by BICD1 expression — UCEC

Explore this box plot interactively →