BICD1

Across TCGA cell cohorts, BICD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,863 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BICD1-associated GO terms across cancer lineages are Positive regulation of protein localization to centrosome, Minus-end-directed organelle transport along microtubule, and Constitutive secretory pathway. Each is linked with BICD1 in more than 15 cancer types. Because this analysis shows association rather than direction, both BICD1-to-partner and partner-to-BICD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to centrosome grouped by BICD1-low versus BICD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BICD1→partner) and Y-score (partner→BICD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of protein localization to centrosome →	+0.160	+1.218	<.001	<.001	3	16
LIVER	Minus-end-directed organelle transport along microtubule →	+0.209	+1.126	.001	<.001	3	16
STOMACH	Constitutive secretory pathway →	+0.164	+1.215	<.001	<.001	3	16
BONE	Cortical microtubule organization →	+0.182	+1.079	<.001	.001	3	13
BONE	Regulation of protein localization to centrosome →	+0.127	+1.060	<.001	.002	3	13
LUNG_SCLC	Intracellular mRNA localization →	+0.176	+0.923	<.001	.002	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,863 associations by consensus.

Positive regulation of protein localization to centrosome by BICD1 expression — BONE

Explore this box plot interactively →