BICD1

Across TCGA cell cohorts, BICD1 mutation is significantly associated with the RNA expression of many other genes, with 347 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BICD1-associated genes across cancer lineages are GAGE12H, PZP, and GHRHR. Each is linked with BICD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BICD1-to-partner and partner-to-BICD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12H grouped by BICD1-low versus BICD1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICD1→partner) and Y-score (partner→BICD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	GAGE12H →	+1.264	+4.199	<.001	.007	3	2
BREAST	PZP →	+0.376	+4.421	<.001	.004	3	1
BLOOD_Leukemia	GHRHR →	+0.377	+3.705	<.001	.007	3	1
BLOOD_Leukemia	BTBD16 →	+0.086	+3.959	<.001	.005	3	1
BLOOD_Leukemia	TLX3 →	+1.796	+3.944	<.001	.006	3	1
BLOOD_Leukemia	TBPL2 →	+0.134	+4.044	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 347 associations by consensus.

GAGE12H by BICD1 expression — BREAST

Explore this box plot interactively →