BICC1

Across TCGA patient cohorts, BICC1 mutation is significantly associated with the RNA expression of many other genes, with 5,299 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BICC1-associated genes across cancer lineages are HNRNPF, PDCD2L, and CEP55. Each is linked with BICC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BICC1-to-partner and partner-to-BICC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPF grouped by BICC1-low versus BICC1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICC1→partner) and Y-score (partner→BICC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	HNRNPF →	+0.433	+3.236	.007	.008	3	5
LUSC	PDCD2L →	+0.612	+3.213	.005	.009	3	5
UCEC	CEP55 →	+0.689	+2.209	<.001	<.001	3	5
STAD	MTFP1 →	+0.693	+3.334	<.001	.005	3	4
UCEC	RACGAP1 →	+0.667	+1.638	<.001	<.001	3	4
LUSC	SUCLG1 →	+0.397	+3.459	.006	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,299 associations by consensus.

HNRNPF by BICC1 expression — STAD

Explore this box plot interactively →