BICC1

Across TCGA cell cohorts, BICC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,765 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BICC1-associated GO terms across cancer lineages are SMAD protein signal transduction, Positive regulation of supramolecular fiber organization, and Positive regulation of blood pressure by epinephrine-norepinephrine. Each is linked with BICC1 in more than 11 cancer types. Because this analysis shows association rather than direction, both BICC1-to-partner and partner-to-BICC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMAD protein signal transduction grouped by BICC1-low versus BICC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BICC1→partner) and Y-score (partner→BICC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	SMAD protein signal transduction →	+0.127	+1.915	.003	<.001	3	12
BONE	Positive regulation of supramolecular fiber organization →	+0.073	+2.281	<.001	<.001	3	11
BONE	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.591	+2.562	<.001	<.001	3	10
BONE	Regulation of heart rate by chemical signal →	+0.510	+2.526	<.001	<.001	3	10
BONE	Regulation of focal adhesion assembly →	+0.155	+2.460	<.001	<.001	3	10
BONE	Regulation of cell-substrate junction assembly →	+0.155	+2.460	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,765 associations by consensus.

SMAD protein signal transduction by BICC1 expression — BONE

Explore this box plot interactively →