BICC1

Across TCGA cell cohorts, BICC1 mutation is significantly associated with the RNA expression of many other genes, with 177 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BICC1-associated genes across cancer lineages are OR52E5, OR6V1, and OR13G1. Each is linked with BICC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BICC1-to-partner and partner-to-BICC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52E5 grouped by BICC1-low versus BICC1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICC1→partner) and Y-score (partner→BICC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR52E5 →	+0.020	+4.392	<.001	.004	3	2
LUNG_NSCLC_LUAD	OR6V1 →	+0.014	+3.189	<.001	.007	3	2
LARGE_INTESTINE	OR13G1 →	+0.011	+3.000	<.001	.003	3	2
LARGE_INTESTINE	LACTBL1 →	+0.021	+2.824	.004	.001	3	2
SOFT_TISSUE	TSPO2 →	+0.053	+3.865	.004	.006	3	1
SOFT_TISSUE	MORC1 →	+0.079	+3.635	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 177 associations by consensus.

OR52E5 by BICC1 expression — SOFT_TISSUE

Explore this box plot interactively →