BHMT2

Across TCGA cell cohorts, BHMT2 RNA expression is significantly associated with the RNA expression of many other genes, with 4,051 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BHMT2-associated genes across cancer lineages are DMGDH, BHMT, and AKR1B10. Each is linked with BHMT2 in more than 8 cancer types. Because this analysis shows association rather than direction, both BHMT2-to-partner and partner-to-BHMT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHMT2 versus DMGDH in KIDNEY, with a Pearson correlation of 0.94.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHMT2→partner) and Y-score (partner→BHMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	DMGDH →	+2.636	+4.121	<.001	<.001	3	9
KIDNEY	BHMT →	+1.084	+3.960	.004	<.001	1	6
LIVER	AKR1B10 →	+9.941	+5.499	<.001	<.001	3	4
LUNG_NSCLC_LUSC	TCN2 →	+1.724	+2.673	.002	<.001	3	3
BLOOD_Leukemia	RUFY3 →	+1.355	+0.092	<.001	<.001	3	3
BLOOD_Lymphoma	TOR4A →	+1.509	+0.147	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,051 associations by consensus.

BHMT2 vs DMGDH — KIDNEY

Explore this scatter interactively →