BHMT

Across TCGA patient cohorts, BHMT RNA expression is significantly associated with the protein abundance of many other proteins, with 10,001 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BHMT-associated proteins across cancer lineages are ISG20, VEZF1, and FERMT3. Each is linked with BHMT in more than 4 cancer types. Because this analysis shows association rather than direction, both BHMT-to-partner and partner-to-BHMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHMT versus ISG20 in BRCA, with a Pearson correlation of -0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BHMT→partner) and Y-score (partner→BHMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ISG20 →	-0.560	-0.202	<.001	.004	3	5
CCRCC	VEZF1 →	+0.352	+1.553	<.001	<.001	3	4
GBM	FERMT3 →	-0.433	-0.402	.007	.004	3	4
HNSC	HNRNPU →	+0.220	+0.461	<.001	.004	3	4
HNSC	UBXN7 →	+0.514	+0.577	<.001	<.001	3	3
HNSC	USP15 →	-0.213	-0.555	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,001 associations by consensus.

BHMT vs ISG20 — BRCA

Explore this scatter interactively →