BHLHE23

Across TCGA patient cohorts, BHLHE23 protein abundance is significantly associated with the RNA expression of many other genes, with 5,177 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BHLHE23-associated genes across cancer lineages are SMARCC1, TOM1, and CSNK1A1. Each is linked with BHLHE23 in more than 2 cancer types. Because this analysis shows association rather than direction, both BHLHE23-to-partner and partner-to-BHLHE23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHLHE23 versus SMARCC1 in UCEC, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE23→partner) and Y-score (partner→BHLHE23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SMARCC1 →	-0.780	-1.083	.001	<.001	3	3
OV	TOM1 →	+0.733	+0.745	.006	.008	3	2
OV	CSNK1A1 →	+0.730	+0.782	.009	.004	3	2
LSCC	PFDN2 →	-0.627	-0.769	<.001	.001	3	2
HNSC	CSGALNACT1 →	+1.276	+0.903	.001	.004	3	2
OV	TNFRSF10C →	+0.877	+0.869	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,177 associations by consensus.

BHLHE23 vs SMARCC1 — UCEC

Explore this scatter interactively →