BHLHE23

Across TCGA patient cohorts, BHLHE23 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. COAD shows the largest number of these associations.

The most reproducible BHLHE23-associated genes across cancer lineages are SNORD113-4, RNU6-1054P, and LINC01826. Each is linked with BHLHE23 in more than 1 cancer types. Because this analysis shows association rather than direction, both BHLHE23-to-partner and partner-to-BHLHE23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD113-4 grouped by BHLHE23-low versus BHLHE23-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE23→partner) and Y-score (partner→BHLHE23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNORD113-4 →	+1.287	+5.541	<.001	<.001	3	1
COAD	RNU6-1054P →	+0.859	+3.993	<.001	.005	3	1
COAD	LINC01826 →	+0.099	+5.136	<.001	.002	3	1
COAD	VENTXP7 →	+0.184	+4.868	<.001	<.001	3	1
COAD	MIR4314 →	+0.354	+5.332	<.001	.002	3	1
COAD	UBE2Q2P6 →	+0.124	+4.428	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

SNORD113-4 by BHLHE23 expression — COAD

Explore this box plot interactively →