BHLHE23

Across TCGA cell cohorts, BHLHE23 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,025 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BHLHE23-associated GO terms across cancer lineages are Regulation of hemostasis, Skin development, and Mammary gland involution. Each is linked with BHLHE23 in more than 3 cancer types. Because this analysis shows association rather than direction, both BHLHE23-to-partner and partner-to-BHLHE23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hemostasis grouped by BHLHE23-low versus BHLHE23-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE23→partner) and Y-score (partner→BHLHE23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of hemostasis →	-0.084	-0.605	<.001	.002	3	4
SOFT_TISSUE	Skin development →	-0.093	-0.019	.004	.006	3	4
SOFT_TISSUE	Mammary gland involution →	-0.193	-0.028	<.001	.003	3	4
SOFT_TISSUE	Negative regulation of double-strand break repair via homologous recombination →	+0.078	+0.025	.001	.008	3	4
SOFT_TISSUE	DNA strand elongation →	+0.103	+0.024	.001	.006	3	4
BLOOD_Leukemia	Regulation of metaphase/anaphase transition of cell cycle →	+0.062	+0.606	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,025 associations by consensus.

Regulation of hemostasis by BHLHE23 expression — BLOOD_Leukemia

Explore this box plot interactively →