BHLHE22

Across TCGA patient cohorts, BHLHE22 RNA expression is significantly associated with the RNA expression of many other genes, with 11,954 significant associations in total. PAAD shows the largest number of these associations.

The most reproducible BHLHE22-associated genes across cancer lineages are CYP7B1, ACKR1, and OLFML1. Each is linked with BHLHE22 in more than 26 cancer types. Because this analysis shows association rather than direction, both BHLHE22-to-partner and partner-to-BHLHE22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHLHE22 versus CYP7B1 in LAML, with a Pearson correlation of 0.48.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE22→partner) and Y-score (partner→BHLHE22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	CYP7B1 →	+1.973	+0.281	<.001	<.001	3	27
CHOL	ACKR1 →	+3.481	+0.946	<.001	<.001	3	26
BLCA	OLFML1 →	+1.308	+0.645	<.001	<.001	3	25
CHOL	CCDC69 →	+1.993	+1.214	<.001	<.001	3	25
CHOL	IGLV2-11 →	+3.108	+0.845	<.001	<.001	3	25
STAD	MYLK →	+2.030	+0.921	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,954 associations by consensus.

BHLHE22 vs CYP7B1 — LAML

Explore this scatter interactively →