BHLHE22

Across TCGA patient cohorts, BHLHE22 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,948 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BHLHE22-associated proteins across cancer lineages are WIPF1, ZCCHC24, and SEPTIN1. Each is linked with BHLHE22 in more than 7 cancer types. Because this analysis shows association rather than direction, both BHLHE22-to-partner and partner-to-BHLHE22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHLHE22 versus WIPF1 in OV, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE22→partner) and Y-score (partner→BHLHE22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WIPF1 →	+0.495	+0.660	<.001	<.001	3	8
OV	ZCCHC24 →	+0.869	+0.780	<.001	<.001	3	8
OV	SEPTIN1 →	+0.683	+0.675	<.001	<.001	3	7
HNSC	SGCD →	+0.774	+0.729	<.001	.001	3	7
GBM	CACNA2D1 →	+0.537	+0.643	<.001	.005	3	7
OV	CNRIP1 →	+0.659	+0.594	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,948 associations by consensus.

BHLHE22 vs WIPF1 — OV

Explore this scatter interactively →